PICS Organization Name
National Institutes of Heath (NIAID/NIH)
Catherina Pan '18, Cristin Park '18, Pranav Rekapalli '20, Alicia Wang '19, Daniela Coronado '19
NIH is the National Institutes of Health, the arm of the federal government devoted to improving the national and international health through scientific discovery. For more information about NIH, please go here: http://www.nih.gov/
NIH is a federal agency devoted to improving human health through scientific research. The NIH has over 20,000 employees and over 1000 laboratories all devoted to biomedical research. The NIH is a leader in developing new knowledge related to biological systems and human disease, including new concepts of disease pathogenesis, risk factors, diagnostics, therapeutics and preventive measures.
Our current laboratory studies basic and clinical immunology, with a particular emphasis on mechanisms of leukocyte trafficking. We have had research projects in many areas, including allergy, infectious disease, inflammation, both at the basic and clinical levels, and in specific diseases such as HIV, West Nile virus, atherosclerosis, primary immunodeficiency and transplantation. Currently we have emphasized the work on transplantation and a rare immunodeficiency disease known as WHIM syndrome.
The exact project will depend on the student's interests and abilities. The range of options all involve molecular and cell biology techniques as well as work with mouse models. Currently, the lab is working on an inherited immunodeficiency disease known as WHIM syndrome and is developing novel, drug, gene therapy (CRISPR/CAS9) and allotransplantation methods for treating and eventually curing the patients. The research is conducted in mouse models as well as in a cohort of 40 patients with this rare disease. The lab also studies pathogenesis of the protozoan Trypanosoma cruzi and the herpesvirus mouse cytomegalovirus. Students interested in a career in medicine and especially in biomedical research will find relevant projects in the lab's research portfolio.
Required: Curiosity, patience, passion for discovery, desire to alleviate human suffering
Expected Start Time
Expected End Time
Meets Certificate Requirement
Yes, Global Health Policy
The NIH website www.nih.gov has information regarding housing. Lab postdocs and postbacs can be contacted to help locate a suitable place.
US government background check and health exam are required. US citizenship required.
The National Institutes of Health (NIH) is an organization whose mission is to improve health care of patients, regardless of how rare or common their conditions are. Starting from the molecular level, all the way to patience care, the NIH creates valuable knowledge that will benefit millions of patients not just in the United States, but also around the world. As summer interns, we were to witness the NIH's mission being fulfilled by taking part in it. Under the guidance of our mentors and supervisors, we conducted novel research that one day will benefit the health care of patients. Being able to participate in this mission was truly an eye-opening experience I will always cherish.
— Daniela Coronado '19
I worked on a preclinical project in the lab. We were developing a cure for a rare disease known as WHIM syndrome through gene therapy. I ran experiments to edit the genes of mouse immune cells and determine if this editing was successful using flow cytometry and DNA analysis. I liked learning new techniques and also using biological lab techniques to benefit the health of others.
—Alicia Wang '19